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Product Name: 2-nmc
IUPAC Name: 3,4-Dimethoxy-N-methylamphetamine (DMMA)
Other Names: DMMA
Cas Number:
Molecular Formula: C12H19NO2
Molar Mass: 209.289 g·mol−1
Effect: stimulant, psychedelic
Purity of the substance: ≥99.9%
Physical properties: Crystals
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What is DMMA

Dimethoxymethamphetamine (DMMA) emerges as a captivating and intricate member within the realm of psychoactive compounds. With its elaborate chemical architecture and potential psychoactive properties, DMMA has captured the attention of both the scientific community and enthusiasts of recreational substances. This article delves comprehensively into the multifaceted domain of DMMA, its origins, effects, dosing considerations, legal standing, pharmacology, and chemistry.

Acquiring Dimethoxymethamphetamine (DMMA)

Procuring DMMA through legitimate avenues is a rarity, given its production and distribution frequently operate outside established regulatory frameworks. Consequently, it tends to be associated with illicit markets, posing substantial risks to those seeking acquisition or usage. The absence of quality control and oversight in these underground markets exacerbates the hazards of obtaining DMMA.

Dimethoxymethamphetamine (DMMA) in Context

Dimethoxymethamphetamine (DMMA), also known by its chemical identifier 2,5-dimethoxy-4-methylamphetamine, stands as a derivative of methamphetamine. It fits structurally within the amphetamine category of compounds and shares structural affinities with other psychoactive substances such as MDMA and MDA. The compound's chemical blueprint comprises a phenethylamine foundation with a phenyl ring and an amine group. Added methoxy (CH3O) groups are strategically affixed to specific positions, further enriching its complexity.

The Historical Trajectory of Dimethoxymethamphetamine (DMMA)

DMMA's historical narrative is entwined with exploring psychedelic and psychoactive agents. Its origins trace back to investigating chemical alterations to amphetamine derivatives aimed at evoking distinct psychoactive responses. Although it may not have garnered the same prominence as its counterparts like MDMA, DMMA's history is intertwined with the broader pursuit of unraveling the human mind and consciousness through chemical avenues.

Effects of Dimethoxymethamphetamine (DMMA)

The psychoactive outcomes of DMMA have not undergone as extensive scrutiny as those of more recognized substances. Nevertheless, akin to other amphetamine derivatives, it is believed to induce stimulating and empathogenic effects on the central nervous system. Users have reported shifts in mood, sensory perception, and heightened sociability. Anecdotal evidence suggests that DMMA might also elicit visual distortions and mild hallucinations, though the intensity of these effects varies across individuals.

Navigating Dimethoxymethamphetamine (DMMA) Dosages

Due to insufficient scientific exploration, establishing a safe and productive DMMA dosage is a formidable task. Furthermore, the potency and purity of illicitly sourced DMMA can diverge significantly, leading to unpredictability in its effects. Individuals who engage with DMMA often resort to dosage experimentation, amplifying the risk of adverse reactions and potential overdose. Given the peril associated with DMMA use, the exploration of this compound, along with other psychoactive substances, is strongly discouraged.

The Legal Status of Dimethoxymethamphetamine (DMMA)

As of the knowledge cutoff in September 2021, DMMA is likely classified as a controlled substance across numerous jurisdictions. However, the legal standing of psychoactive agents can shift swiftly, necessitating readers to consult current legal resources within their respective regions. The classification of DMMA as a controlled substance mirrors concerns about its susceptibility to abuse, absence of medical utility, and associated health hazards.

The Pharmacological Underpinnings of Dimethoxymethamphetamine (DMMA)

The pharmacological mechanisms that underlie MDMA's effects remain partially obscured. Similar to other amphetamine derivatives, it is postulated that DMMA exerts its influence by augmenting the release of neurotransmitters like dopamine, norepinephrine, and serotonin in the brain. These neurotransmitters are pivotal in regulating mood, arousal, and sensory perception. The supplementary methoxy groups in DMMA's chemical configuration may contribute to its distinctive pharmacological profile, potentially impacting receptor binding and activity.

Unveiling the Chemistry of Dimethoxymethamphetamine (DMMA)

DMMA's chemical makeup showcases its connection to the amphetamine and phenethylamine classifications. Including two methoxy groups (CH3O) affixed at precise positions on the phenyl ring is the basis for its vocabulary, denoting their arrangement at the 2 and 5 positions. This structural configuration shapes the compound's interactions with receptors and enzymes within the brain, potentially accounting for its psychoactive effects. The intricate interplay between DMMA's structure and biological reactivity remains pivotal to ongoing investigations.


Dimethoxymethamphetamine (DMMA) emerges as an enthralling subject of exploration within the sphere of psychoactive compounds. Its intricate chemical framework, potential effects, and accompanying risks captivate the attention of researchers, healthcare practitioners, and policymakers. Nevertheless, owing to its limited research and association with illicit markets, DMMA's true essence continues to shroud itself in mystery. As comprehension of the compound progresses, it is imperative to approach it prudently, stressing the significance of well-informed choices and prioritizing safety and well-being.

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