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α-Pyrrolidinopentiophenone, also known as α-pyrrolidinovalerophenone, α-PVP, O-2387, β-keto-prolintane, prolintanone, or desmethyl pyrovalerone, is a synthetic stimulant drug that belongs to the cathinone class of drugs. This substance was created in the 1960s, and its use as a designer drug has been widespread. Commonly, the name "flakka" refers to α-PVP, which is chemically linked to pyrovalerone and is the ketone analogue of prolintane.
History of α-Pyrrolidinopentiophenone
In the 1960s, α-Pyrrolidinopentiophenone was initially produced as part of the cathinone pharmacological class research. Initially, it was used as a medicinal medicine to treat various medical disorders, including attention deficit hyperactivity disorder (ADHD) and narcolepsy. Due to its significant potential for addiction and severe side effects, the medicine was finally discontinued. In recent years, α-PVP has gained popularity as a designer drug with psychotropic and stimulating properties.
The Effects of α-Pyrrolidinopentiophenone
α-Pyrrolidinopentiophenone is a powerful stimulant substance with a variety of physiological effects. α-PVP causes an accelerated heart rate, raised blood pressure, reduced hunger, and euphoria. Additionally, the medicine has various adverse effects, including agitation, paranoia, hallucinations, and violence. In addition, the substance can be very addictive, and discontinuing it abruptly may result in withdrawal symptoms.
The Legal Status of α-Pyrrolidinopentiophenone
In the United States, α-Pyrrolidinopentiophenone is categorized as a Schedule I controlled substance, which makes its manufacturing, distribution, and possession unlawful. In several other nations, including the United Kingdom, Australia, and Canada, the medication is similarly categorized as a restricted substance. α-PVP is extensively available on the black market, where it is offered as a designer drug despite its categorization as a banned narcotic.
The Dangers of α-Pyrrolidinopentiophenone
α-Pyrrolidinopentiophenone is a highly toxic medication associated with various severe health consequences, including overdose and death. The substance has a significant potential for misuse, and those who use it are at risk for various mental and physical health issues, including addiction, depression, and cardiovascular disease. In addition, the medication may have long-term effects on the brain and neurological system, and continuous usage may result in cognitive and memory deficits.
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To prepare the content, the following materials were used:
- FDA Substance Registration System
- Hazardous Substances Data Bank. National Library of Medicine. 28 August 2008. Retrieved 22 August 2014. 3,4-Methylenedioxymethamphetamine
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