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For their stimulating and euphoric effects, stimulant medications have been widely used and misused. With the growth of designer pharmaceuticals, several novel chemicals have entered the market, necessitating a greater understanding of their characteristics, effects, and hazards. In this article, we shall cover the stimulants 4-Fluorométhamphetamine (4-FMA) and 2-Fluorométhamphetamine (2-FMA), both of which have reportedly been marketed as designer medications.
What is 4-Fluoromethamphetamine (4-FMA)?
4-Fluoromethamphetamine (4-FMA) is an analogue of methamphetamine and 4-fluoro amphetamine. In 2006, it was first found in legal highs marketed in Japan, and in 2008, it became illegal to sell or possess for distribution purposes (though not for personal use) in Japan. Despite being a controlled substance, 4-FMA is reportedly offered as a designer drug and abused for its stimulating and euphoric effects.
What is 2-Fluoromethamphetamine (2-FMA)?
2-Fluoromethamphetamine (2-FMA) is a stimulant substance of the amphetamine family used as a designer drug. Comparable to lisdexamfetamine (Vyvanse) and dextroamphetamine in terms of its effectiveness as a study or productivity aid. Due to its primary mechanism of action, which is the suppression of norepinephrine reuptake, it is believed that 2-FMA produces somewhat less euphoria than similar amphetamines.
What do we know about 4-FMA and 2-FMA's pharmacology and toxicology?
Even though 4-FMA and 2-FMA are widely utilized, little is known regarding their pharmacology and toxicity. As with many designer drugs, few studies have been undertaken on these compounds, and the majority of the available information is based on anecdotal data from users. However, the absence of study on these compounds emphasizes the significance of exercising caution while utilizing any new or unknown substances since they may have harmful or fatal effects.
How are 4-FMA and 2-FMA used?
4-FMA and 2-FMA are commonly administered orally or nasally but can alternatively be injected. Similar to other stimulants, the effects of these medicines include enhanced alertness, energy, and pleasure. Due to a shortage of studies, these compounds' precise effects, doses, and possible hazards still need to be fully understood.
What are the dangers of using 4-FMA and 2-FMA?
There are a variety of possible risks linked with the use of 4-FMA and 2-FMA, as with any stimulant medicines. Among these risks are anxiety, paranoia, hostility, cardiovascular issues, and the possibility of overdose. In addition, because these medications are not controlled, there is a possibility of impurities in the drugs, which might result in severe health complications.
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To prepare the content, the following materials were used:
- FDA Substance Registration System
- Hazardous Substances Data Bank. National Library of Medicine. 28 August 2008. Retrieved 22 August 2014. 3,4-Methylenedioxymethamphetamine
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