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4F-MPH is a stimulant drug that acts as a higher potency dopamine reuptake inhibitor than the closely related methylphenidate. 4-Fluoromethylphenidate (4F-MPH) was studied further along with other analogs of (±)-three-methylphenidate (TMP) to assess their potential as anti-cocaine medications. 4F-MPH was reported as having an ED50 mg/kg of 0.26 (0.18–0.36), regarding its efficacy as a substitute for cocaine and a relative potency of 3.33 compared to methylphenidate for the same purpose. This is based on its binding strength to the dopamine transporter vs. its activity as a dopamine reuptake inhibitor. In theory, this would block some of the effects of cocaine without being as addictive."
4-Fluoromethylphenidate (4F-MPH) is a stimulant drug with a higher potency dopamine reuptake inhibitor than the closely related methylphenidate. 4-Fluoromethylphenidate was studied further along with other analogs of (±)-three-methylphenidate (TMP) to assess their potential as anti-cocaine medications.
4-Fluoromethylphenidate (also known as 4-FMPH and 4F-MPH) is a stimulant drug that acts as a more potent dopamine reuptake inhibitor than the closely related methylphenidate. Unlike cocaine, it has a limited effect on norepinephrine reuptake, making it less likely to be addictive in humans.
4-Fluoromethylphenidate (also known as 4-FMPH and 4F-MPH) is a stimulant drug with properties similar to methylphenidate. Unlike cocaine, however, it has a limited effect on the reuptake of norepinephrine, making it less likely to be addictive in humans.
4-Fluoromethylphenidate is a synthetic stimulant of the phenethylamine class that produces a combination of entactogenic and stimulant effects when administered.
4-Fluoromethylphenidate (also known as 4-FMPH and 4F-MPH) is a prescription medication for treating attention deficit hyperactivity disorder (ADHD).
The drug has barely ever been seen in humans, so there is little knowledge of its effects on humans. Clinical trials are needed to investigate the pharmacological action and potential use in humans.
Following the discovery of methylphenidate (Ritalin) as a cocaine substitute and its subsequent widespread clinical use as a treatment for ADHD or narcolepsy, many other related stimulants were subsequently investigated as substitution agents for cocaine. One of these was [4-(±)-threo]-methylphenidate (TMP).
It is a chemical substance belonging to the class of phenethylamine derivatives (including substituted amphetamines, methylphenidates, and cathinone) and possesses stimulant effects. The drug has been reported as a novel psychoactive substance, being sold as a designer drug in various countries. It is also used for recreational purposes like other stimulants.
It is a chemical substance belonging to the class of phenethylamine derivatives (including substituted amphetamines, methylphenidates, and cathinone) and possesses stimulant effects. The drug has been reported as a novel psychoactive substance, being sold as a designer drug in various countries.
Methamphetamine, also known as "meth," is a drug that belongs to the class of substituted amphetamines. It has stimulant effects and is sometimes considered to possess psychedelic and euphoric properties.
To prepare the content, the following materials were used:
- FDA Substance Registration System
- Hazardous Substances Data Bank. National Library of Medicine. 28 August 2008. Retrieved 22 August 2014. 3,4-Methylenedioxymethamphetamine
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