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Specification
IUPAC Name: 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
Cas Number: 139755-83-2
Molecular Formula: C22H30N6O4S
Molar Mass: 474.5 g/mol
Effect: stimulant
Physical properties: pills
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Sildenafil, sold as Viagra, among other names, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. Sildenafil is taken by mouth or by injection into a vein. It typically starts working in 20 minutes and lasts for about two hours. Common side effects include headaches and heartburn. Caution is advised for those with cardiovascular disease. Rare but serious side effects include prolonged erection (priapism), which can damage the penis. Sildenafil should not be taken by people on nitrates such as glycerin trinitrate (nitroglycerin), as this may result in a serious drop in blood pressure.

Sildenafil, sold under the brand names Viagra and Revatio and many other trade names, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is unclear if it is effective for treating sexual dysfunction in women. The mechanism of action is as an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), which relaxes smooth muscles in the trabecular arteries and corpus cavernosum.

Sildenafil (marketed as Viagra and Revatio) is a drug used to treat erectile dysfunction and pulmonary arterial hypertension. It has not been proven to work in women. It works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5).

Sildenafil is an effective medication for erectile dysfunction in men and pulmonary arterial hypertension.

Sildenafil can be used to treat both men and women.

Sildenafil is often used to treat erectile dysfunction and pulmonary arterial hypertension. It is unclear if it is effective for treating sexual dysfunction in women. The FDA categorized sildenafil as a PDE5 inhibitor, the same class of drugs as Viagra (sildenafil).

Sildenafil is a relatively new drug that has been shown to effectively treat erectile dysfunction in men and pulmonary arterial hypertension (PAH). Also known as “Viagra” and generic sildenafil citrate, it’s a medication made of citrate salts.

Sildenafil citrate is a member of the PDE5 inhibitor class, which is a type of vasodilator. Sildenafil treats erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It works by relaxing muscles in the walls of blood vessels supplying the penis, allowing more blood to enter the penis and resulting in an erection. This makes it easier for men to get and maintain an erection during sexual stimulation.

Sildenafil belongs to a group of medications known as PDE5 inhibitors, which affect the ability of PDE5 to break down an erection-causing chemical. It is used to treat erectile dysfunction and pulmonary arterial hypertension. This drug causes the blood vessels in your penis to dilate, allowing it to fill with blood, thus causing an erection.

Sildenafil is a phosphodiesterase-5 (PDE5) inhibitor developed by Pfizer in 1992. It was originally used as a cardiovascular medication to treat post-heart surgery angina and chest pain. It also treats PAH and erectile dysfunction by increasing blood flow to the penis. It works by blocking PDE5, thereby preventing it from breaking down cyclic guanosine monophosphate (cGMP), which causes smooth muscle relaxation in the penis.

Sildenafil treats erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Sildenafil may also be used to treat male hypogonadism. This medication should not be used to prevent heart attacks and strokes or relieve chest pain caused by clogged arteries; other drugs are available for those purposes. Sildenafil does not protect against sexually transmitted diseases such as HIV infection (AIDS) and gonorrhea.

Sildenafil is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is unclear if it is effective for treating sexual dysfunction in women.

Sildenafil is used to treat pulmonary arterial hypertension, erectile dysfunction and other conditions as determined by your physician.

To prepare the content, the following materials were used:

  1. FDA Substance Registration System
  2. Hazardous Substances Data Bank. National Library of Medicine. 28 August 2008. Retrieved 22 August 2014. 3,4-Methylenedioxymethamphetamine
  3. Liver transplant modulates gut microbial dysbiosis and cognitive function in cirrhosis. PDF . By HoChong Gilles, Scott C Matherly, Mohammed S Siddiqui, Puneet Puri...
  4. Differential impact of hyponatremia and hepatic encephalopathy on health-related quality of life and brain metabolite abnormalities in cirrhosis . By Jasmohan Bajaj
  5. An overview of alcohol and other drug issues
  6. Medicating the mind: a Kantian analysis of overprescribing psychoactive drugs B A Manninen
  7. The pharmacological basis of opioids Carla Ghelardini, Lorenzo Di Cesare Mannelli and Enrica Bianchi
  8. Ask Dr. Shulgin Online ARCHIVE: June 3, 2004
  9. Inhibition of plasma membrane monoamine transporters by β-ketoamphetamines. Nicholas V Cozzi, Michael KSievert, Alexander T Shulgin, Peyton JacobIII, Arnold Eruoho
  10. Schedules of Controlled Substances: Placement of Methylone Into Schedule I
  11. Bioanalysis of new designer drugs. Wohlfarth A, Weinmann W.
  12. New Psychoactive Substances (including synthetic cannabinoids, mephedrone, and more)
  13. Future Synthetic Drugs of Abuse. Donald A. Cooper. Drug Enforcement Administration McLean, Virginia
  14. Designer drugs: a medicinal chemistry perspective. F. Ivy Carroll Anita H. Lewin S. Wayne Mascarella Herbert H. Seltzman P. Anantha Reddy
  15. Synthetic cannabinoids in Europe
  16. Pharmacological Effects of MDMA in Man. By Enno Freye
  17. Drug Use in Relation to Outcome of Mammography Screening. von Euler-Chelpin M, Wu W, Vejborg and Lynge E
  18. DEA Drug Scheduling
  19. Electrophysiological Effects of Trace Amines on Mesencephalic Dopaminergic Neurons.Ada Ledonne, Nicola Berretta, Alessandro Davoli, Giada Ricciardo Rizzo, Giorgio Bernardi and Nicola Biagio Mercuri
  20. Electrophysiological evidence for a reciprocal interaction between amphetamine and cocaine-related drugs on rat midbrain dopaminergic neurons.Scarponi M, Bernardi G, Mercuri NB.
  21. Overdose of Drugs for Attention-Deficit Hyperactivity Disorder: Clinical Presentation, Mechanisms of Toxicity, and Management. Henry A. Spiller, author Hannah L. Hays Alfred Aleguas.
  22. Dose-dependent effectiveness of wheel running to attenuate cocaine-seeking: impact of sex and estrous cycle in rats. Peterson AB, Hivick DP, Lynch WJ.r.
  23. FDA Drug Safety Communication: Safety Review Update of Medications used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in children and young adults
  24. ADHD Medications and Risk of Serious Cardiovascular Events in Young and Middle-aged Adults
  25. Controlled Substances Act
  26. The Art of Drug Synthesis (Wiley Series on Drug Synthesis)
  27. Cannabis: domestic cultivation widespread
  28. A review of the influence of functional group modifications to the core scaffold of synthetic cathinones on drug pharmacokinetics
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